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规格：
查看说明书Caldesmon Rabbit pAb
Cat#:DPA02153应用：WB,IHC
| Product Name: | Phospho-Caldesmon/CDM (Ser759) Rabbit pAb |
| Cat No.: | DPA05404 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB |
| Recommended Dilution: | WB: 1:1000 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic phosphopeptide corresponding to residues surrounding Ser759 of human Caldesmon/CDM |
| Calculated Molecular Weight: | 93 kDa |
| Observed Molecular Weight: | 80 kDa |
| GenBank Accession Number: | Q05682 |
| Gene ID (NCBI): | 800 |
| Synonyms: | CDM; HCAD; LCAD; H-CAD; L-CAD; NAG22 |
| Background: | This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008] |
| Category: | Primary Ab |
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