Acetyl Coenzyme A Carboxylase Rabbit pAb
Cat#:DPA02528应用:WB,IHC,ICC/IF,FC
| Product Name: | Phospho-Acetyl Coenzyme A Carboxylase (Ser79) Rabbit pAb | 
| Cat No.: | DPA05539 | 
| Clonality: | Polyclonal | 
| Species Reactivity: | Human, Mouse, Rat | 
| Tested Applications: | WB | 
| Recommended Dilution: | WB: 1:1000-1:5000 | 
| Size: | 30ul 50ul 100uL | 
| Format: | Liquid | 
| Source: | Rabbit | 
| Purification Method: | Affinity Purification | 
| Isotype: | IgG | 
| Conjugate: | Un-conjugated | 
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a | 
| Immunogen: | A synthetic phosphopeptide corresponding to residues surrounding Ser79 of human Acetyl Coenzyme A Ca | 
| Calculated Molecular Weight: | 277 kDa | 
| Observed Molecular Weight: | 277 kDa | 
| GenBank Accession Number: | O00763 | 
| Gene ID (NCBI): | 31 | 
| Synonyms: | ACC; ACAC; ACC1; ACCA; ACACAD | 
| Background: | Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008] | 
| Category: | Primary Ab |