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查看说明书Phospho-ATR (Ser428) Rabbit pAb
Cat#:DPA05545应用：WB
| Product Name: | Phospho-ATR (Ser428) Rabbit pAb |
| Cat No.: | DPA05545 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB |
| Recommended Dilution: | WB: 1:1000-1:5000 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic phosphopeptide corresponding to residues surrounding Ser428 of human ATR |
| Calculated Molecular Weight: | 301 kDa |
| Observed Molecular Weight: | 301 kDa |
| GenBank Accession Number: | Q13535 |
| Gene ID (NCBI): | 545 |
| Synonyms: | FRP1; MEC1; SCKL; FCTCS; SCKL1 |
| Background: | The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1. [provided by RefSeq, Aug 2017] |
| Category: | Primary Ab |
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