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Phospho-INSR/IGF-1R (Tyr1166) Rabbit pAb

Cat No.: DPA05582
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Product Name: Phospho-INSR/IGF-1R (Tyr1166) Rabbit pAb
Cat No.: DPA05582
Clonality: Polyclonal
Species Reactivity: Human, Mouse, Rat
Tested Applications: WB,IP
Recommended Dilution: WB: 1:1000
IP: 1:20
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic phosphopeptide corresponding to residues surrounding Tyr1166 of human INSR/IGF-1R
Calculated Molecular Weight: 155 kDa
Observed Molecular Weight: 95 kDa
GenBank Accession Number: P08069
Gene ID (NCBI): 3480
Synonyms: IGFR; CD221; IGFIR; JTK13
Background: This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]
Category: Primary Ab
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