Recombinant Human IGF1R / CD221 Protein (His tag)
Cat#:TP08380应用:Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | Phospho-INSR/IGF-1R (Tyr1166) Rabbit pAb |
| Cat No.: | DPA05582 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB,IP |
| Recommended Dilution: | WB: 1:1000 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic phosphopeptide corresponding to residues surrounding Tyr1166 of human INSR/IGF-1R |
| Calculated Molecular Weight: | 155 kDa |
| Observed Molecular Weight: | 95 kDa |
| GenBank Accession Number: | P08069 |
| Gene ID (NCBI): | 3480 |
| Synonyms: | IGFR; CD221; IGFIR; JTK13 |
| Background: | This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014] |
| Category: | Primary Ab |