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分子生物学
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查看说明书Recombinant Protein Kinase C Epsilon (PKCe)
Cat#:TP05447应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | Phospho-PKC epsilon (Ser729) Rabbit pAb |
| Cat No.: | DPA05587 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Rat |
| Tested Applications: | WB |
| Recommended Dilution: | WB: 1:1000 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic phosphopeptide corresponding to residues surrounding Ser729 of human PKC epsilon |
| Calculated Molecular Weight: | 84 kDa |
| Observed Molecular Weight: | 84 kDa |
| GenBank Accession Number: | Q02156 |
| Gene ID (NCBI): | 5581 |
| Synonyms: | PKCE; nPKC-epsilon |
| Background: | Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been shown to be involved in many different cellular functions, such as neuron channel activation, apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior. [provided by RefSeq, Jul 2008] |
| Category: | Primary Ab |
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