Recombinant Human VASP Protein
Cat#:TP04458应用:Positive Control; Immunogen; SDS-PAGE; WB
Product Name: | Phospho-VASP (Ser156) Rabbit pAb |
Cat No.: | DPA05593 |
Clonality: | Polyclonal |
Species Reactivity: | Human, Mouse |
Tested Applications: | WB,IHC |
Recommended Dilution: | WB: 1:1000 IHC: 1:50 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic phosphopeptide corresponding to residues surrounding Ser156 of human VASP |
Calculated Molecular Weight: | 40 kDa |
Observed Molecular Weight: | 40 kDa |
GenBank Accession Number: | P50552 |
Gene ID (NCBI): | 7408 |
Synonyms: | Vasodilator-stimulated phosphoprotein |
Background: | Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG. [provided by RefSeq, Jul 2008] |
Category: | Primary Ab |