Recombinant Human VASP Protein
Cat#:TP04458应用:Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | Phospho-VASP (Ser156) Rabbit pAb |
| Cat No.: | DPA05593 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse |
| Tested Applications: | WB,IHC |
| Recommended Dilution: | WB: 1:1000 IHC: 1:50 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic phosphopeptide corresponding to residues surrounding Ser156 of human VASP |
| Calculated Molecular Weight: | 40 kDa |
| Observed Molecular Weight: | 40 kDa |
| GenBank Accession Number: | P50552 |
| Gene ID (NCBI): | 7408 |
| Synonyms: | Vasodilator-stimulated phosphoprotein |
| Background: | Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG. [provided by RefSeq, Jul 2008] |
| Category: | Primary Ab |