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Phospho-VASP (Ser156) Rabbit pAb

Cat No.: DPA05593
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Product Name: Phospho-VASP (Ser156) Rabbit pAb
Cat No.: DPA05593
Clonality: Polyclonal
Species Reactivity: Human, Mouse
Tested Applications: WB,IHC
Recommended Dilution: WB: 1:1000
IHC: 1:50
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic phosphopeptide corresponding to residues surrounding Ser156 of human VASP
Calculated Molecular Weight: 40 kDa
Observed Molecular Weight: 40 kDa
GenBank Accession Number: P50552
Gene ID (NCBI): 7408
Synonyms: Vasodilator-stimulated phosphoprotein
Background: Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG. [provided by RefSeq, Jul 2008]
Category: Primary Ab
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