蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书LRP6 Rabbit pAb
Cat#:DPA01431应用：WB
| Product Name: | Phospho-LRP6 (Ser1490) Rabbit pAb |
| Cat No.: | DPA05598 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB |
| Recommended Dilution: | WB: 1:1000 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic phosphopeptide corresponding to residues surrounding Ser1490 of human LRP6 |
| Calculated Molecular Weight: | 180 kDa |
| Observed Molecular Weight: | 180 kDa |
| GenBank Accession Number: | O75581 |
| Gene ID (NCBI): | 4040 |
| Synonyms: | ADCAD2; STHAG7 |
| Background: | This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.[provided by RefSeq, Dec 2009] |
| Category: | Primary Ab |
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