p95 NBS1 Rabbit pAb
Cat#:DPA01248应用:WB,IHC,ICC/IF,FC,IP
| Product Name: | Phospho-p95 NBS1 (Ser432) Rabbit pAb |
| Cat No.: | DPA05665 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse |
| Tested Applications: | IHC |
| Recommended Dilution: | IHC: 1:50 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic phosphopeptide corresponding to residues surrounding Ser432 of human p95 NBS1 |
| Calculated Molecular Weight: | 85 kDa |
| GenBank Accession Number: | O60934 |
| Gene ID (NCBI): | 4683 |
| Synonyms: | ATV; NBS; P95; NBS1; AT-V1; AT-V2 |
| Background: | Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq, Jul 2008] |
| Category: | Primary Ab |