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查看说明书Phospho-Phospholipase A2 (Ser505) Rabbit pAb
Cat#:DPA05686应用：WB,IP
| Product Name: | Phospho-Phospholipase A2 (Ser505) Rabbit pAb |
| Cat No.: | DPA05686 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse |
| Tested Applications: | WB,IP |
| Recommended Dilution: | WB: 1:1000 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic phosphopeptide corresponding to residues surrounding Ser505 of human Phospholipase A2 |
| Calculated Molecular Weight: | 85 kDa |
| Observed Molecular Weight: | 100 kDa |
| GenBank Accession Number: | P47712 |
| Gene ID (NCBI): | 5321 |
| Synonyms: | cPLA2; PLA2G4; cPLA2-alpha |
| Background: | This gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015] |
| Category: | Primary Ab |
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