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Recombinant Human MAP4K2 / GC Kinase Protein (His & GST tag)

Cat No.: TP08371
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  • 15% SDS-PAGE Reduced

Product Name: Recombinant Human MAP4K2 / GC Kinase Protein (His & GST tag)
Cat No.: TP08371
TargetID: Q12851
Source: Baculovirus-Insect Cells
Gene Accession Number: 5871
Peptide Sequence: Met 1-Tyr 812
Tag: N-His & GST
Purity: >90% as determined by SDS-PAGE.
Formulation: Freeze-dried powder
Storage Buffer: Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose
Storage Condition: Aliquot and store at -20℃ to -80℃ for up to 6 months, buffer containing 50% glycerol is recommen
Category: Protein
Species Reactivity: Human
Predicted Molecular Mass: 119 kDa
Applications: Positive Control; Immunogen; SDS-PAGE; WB
Background: Serine/threonine-protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Acts as a MAPK kinase kinase kinase (MAP4K) and is an upstream activator of the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway and to a lesser extent of the p38 MAPKs signaling pathway. Required for the efficient activation of JNKs by TRAF6-dependent stimuli, including pathogen-associated molecular patterns (PAMPs) such as polyinosine-polycytidine (poly(IC)), lipopolysaccharides (LPS), lipid A, peptidoglycan (PGN), or bacterial flagellin.
Size: 10ug  50ug  100ug  200ug  1mg
Synonyms: BL44;GCK;MAP4K2;RAB8IP
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