Recombinant Human MAP4K2 / GC Kinase Protein (His & GST tag)
Cat#:TP08371应用:Positive Control; Immunogen; SDS-PAGE; WB
Product Name: | Recombinant Human MAP4K2 / GC Kinase Protein (His & GST tag) |
Cat No.: | TP08371 |
TargetID: | Q12851 |
Source: | Baculovirus-Insect Cells |
Gene Accession Number: | 5871 |
Peptide Sequence: | Met 1-Tyr 812 |
Tag: | N-His & GST |
Purity: | >90% as determined by SDS-PAGE. |
Formulation: | Freeze-dried powder |
Storage Buffer: | Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose |
Storage Condition: | Aliquot and store at -20℃ to -80℃ for up to 6 months, buffer containing 50% glycerol is recommen |
Category: | Protein |
Species Reactivity: | Human |
Predicted Molecular Mass: | 119 kDa |
Applications: | Positive Control; Immunogen; SDS-PAGE; WB |
Background: | Serine/threonine-protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Acts as a MAPK kinase kinase kinase (MAP4K) and is an upstream activator of the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway and to a lesser extent of the p38 MAPKs signaling pathway. Required for the efficient activation of JNKs by TRAF6-dependent stimuli, including pathogen-associated molecular patterns (PAMPs) such as polyinosine-polycytidine (poly(IC)), lipopolysaccharides (LPS), lipid A, peptidoglycan (PGN), or bacterial flagellin. |
Size: | 10ug 50ug 100ug 200ug 1mg |
Synonyms: | BL44;GCK;MAP4K2;RAB8IP |