Recombinant Rat Metalloproteinase inhibitor 1 Protein
Cat#:TP02951应用:Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | Recombinant Rat TIMP-1 / TIMP1 Protein |
| Cat No.: | TP08375 |
| TargetID: | P30120 |
| Source: | HEK293 Cells |
| Gene Accession Number: | 116510 |
| Peptide Sequence: | Met1-Ala217 |
| Purity: | >85% as determined by SDS-PAGE. |
| Formulation: | Freeze-dried powder |
| Storage Buffer: | Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose |
| Storage Condition: | Aliquot and store at -20℃ to -80℃ for up to 6 months, buffer containing 50% glycerol is recommen |
| Category: | Protein |
| Species Reactivity: | Rat |
| Predicted Molecular Mass: | 21.5 kDa |
| Applications: | Positive Control; Immunogen; SDS-PAGE; WB |
| Background: | Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling. Also stimulates steroidogenesis by Leydig and ovarian granuloma cells; procathepsin L is required for maximal activity. |
| Size: | 10ug 50ug 100ug 200ug 1mg |
| Synonyms: | TIMP1;Timp-1 |