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规格：
查看说明书Recombinant Human IL-1 Receptor Type 2/IL-1R-2 Protein(C-Fc)
Cat#:TP05038应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | Recombinant Human IL1R2 / IL1RB / CD121b Protein (His tag) |
| Cat No.: | TP08441 |
| TargetID: | P27930 |
| Source: | HEK293 Cells |
| Gene Accession Number: | 7850 |
| Peptide Sequence: | Met 1-Glu 343 |
| Tag: | C-His |
| Purity: | >85% as determined by SDS-PAGE. |
| Formulation: | Freeze-dried powder |
| Storage Buffer: | Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose |
| Storage Condition: | Aliquot and store at -20℃ to -80℃ for up to 6 months, buffer containing 50% glycerol is recommen |
| Category: | Protein |
| Species Reactivity: | Human |
| Predicted Molecular Mass: | 39.3 kDa |
| Applications: | Positive Control; Immunogen; SDS-PAGE; WB |
| Background: | Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competitive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors. |
| Size: | 10ug 50ug 100ug 200ug 1mg |
| Synonyms: | CD121b;CDw121b;IL-1R-2;IL-1RT-2;IL-1RT2;IL1R2c;IL1RB |
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