蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书Eukaryotic Leptin Receptor (LEPR)
Cat#:TP08113应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | Recombinant Human Leptin Receptor / LEPR / CD295 Protein (His & Fc tag) |
| Cat No.: | TP08585 |
| TargetID: | P48357 |
| Source: | HEK293 Cells |
| Gene Accession Number: | 3953 |
| Peptide Sequence: | Met 1-Asp 839 |
| Tag: | C-His & Fc |
| Purity: | >85% as determined by SDS-PAGE. |
| Formulation: | Freeze-dried powder |
| Storage Buffer: | Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose |
| Storage Condition: | Aliquot and store at -20℃ to -80℃ for up to 6 months, buffer containing 50% glycerol is recommen |
| Category: | Protein |
| Species Reactivity: | Human |
| Predicted Molecular Mass: | 121.4 kDa |
| Applications: | Positive Control; Immunogen; SDS-PAGE; WB |
| Background: | On ligand binding, mediates LEP central and peripheral effects through the activation of different signaling pathways such as JAK2/STAT3 and MAPK cascade/FOS. In the hypothalamus, LEP acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones (By similarity) |
| Size: | 10ug 50ug 100ug 200ug 1mg |
| Synonyms: | CD295;LEP-R;LEPRD;OB-R;OBR |
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