蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书Recombinant Mouse Poliovirus Receptor Protein
Cat#:TP05005应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | Recombinant Mouse CSF1R / MCSF Receptor / CD115 Protein (His tag) |
| Cat No.: | TP08595 |
| TargetID: | P09581 |
| Source: | HEK293 Cells |
| Gene Accession Number: | 12978 |
| Peptide Sequence: | Met 1-Ser 511 |
| Tag: | C-His |
| Purity: | >95% as determined by SDS-PAGE. |
| Formulation: | Freeze-dried powder |
| Storage Buffer: | Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose |
| Storage Condition: | Aliquot and store at -20℃ to -80℃ for up to 6 months, buffer containing 50% glycerol is recommen |
| Category: | Protein |
| Species Reactivity: | Mouse |
| Predicted Molecular Mass: | 56.8 kDa |
| Applications: | Positive Control; Immunogen; SDS-PAGE; WB |
| Background: | Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of pro-inflammatory chemokines in response to IL34 and CSF1, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone and tooth development. Required for normal male and female fertility, and for normal development of milk ducts and acinar structures in the mammary gland during pregnancy. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration, and promotes cancer cell invasion. Activates several signaling pathways in response to ligand binding, including the ERK1/2 and the JNK pathway |
| Size: | 10ug 50ug 100ug 200ug 1mg |
| Synonyms: | AI323359;CD115;CSF-1R;Csfmr;Fim-2;Fms;M-CSF-R;M-CSFR |
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