Eukaryotic Cluster Of Differentiation 86 (CD86)
Cat#:TP08527应用:Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | CD86 Rabbit pAb |
| Cat No.: | DPA01173 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB,IHC,ICC/IF,FC,IP |
| Recommended Dilution: | WB: 1:2000 IHC: 1:100 ICC/IF: 1:100 FC: 1:20 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human CD86 |
| Calculated Molecular Weight: | 38 kDa |
| Observed Molecular Weight: | 75 kDa |
| GenBank Accession Number: | P42081 |
| Gene ID (NCBI): | 942 |
| Synonyms: | B70; B7-2; B7.2; LAB72; CD28LG2 |
| Background: | This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011] |
| Category: | Primary Ab |