蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书Epac1 Rabbit pAb
Cat#:DPA01294应用：WB,IHC,ICC/IF,IP
| Product Name: | Epac1 Rabbit pAb |
| Cat No.: | DPA01294 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB,IHC,ICC/IF,IP |
| Recommended Dilution: | WB: 1:2000 IHC: 1:20 ICC/IF: 1:20 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human Epac1 |
| Calculated Molecular Weight: | 104 kDa |
| Observed Molecular Weight: | 104 kDa |
| GenBank Accession Number: | O95398 |
| Gene ID (NCBI): | 10411 |
| Synonyms: | EPAC; EPAC1; bcm910; HSU79275; CAMP-GEFI |
| Background: | Guanine nucleotide exchange factor (GEF) for RAP1A and RAP2A small GTPases that is activated by binding cAMP. Through simultaneous binding of PDE3B to RAPGEF3 and PIK3R6 is assembled in a signaling complex in which it activates the PI3K gamma complex and which is involved in angiogenesis. Plays a role in the modulation of the cAMP-induced dynamic control of endothelial barrier function through a pathway that is independent on Rho-mediated signaling. Required for the actin rearrangement at cell-cell junctions, such as stress fibers and junctional actin. |
| Category: | Primary Ab |
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