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HIF-1-alpha Rabbit pAb

Cat No.: DPA01389
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Product Name: HIF-1-alpha Rabbit pAb
Cat No.: DPA01389
Clonality: Polyclonal
Species Reactivity: Human
Tested Applications: WB,IHC,ICC/IF,FC,IP
Recommended Dilution: WB: 1:1000
IHC: 1:50
ICC/IF: 1:250
FC: 1:50
IP: 1:50
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human HIF-1-alpha
Calculated Molecular Weight: 93 kDa
Observed Molecular Weight: 120 kDa
GenBank Accession Number: Q16665
Gene ID (NCBI): 3091
Synonyms: HIF1; MOP1; PASD8; HIF-1A; bHLHe78; HIF-1alpha; HIF1-ALPHA; HIF-1-alpha
Background: This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2011]
Category: Primary Ab
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