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CCR8 Rabbit pAb

Cat No.: DPA01398
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Product Name: CCR8 Rabbit pAb
Cat No.: DPA01398
Clonality: Polyclonal
Species Reactivity: Human, Mouse, Rat
Tested Applications: WB,ICC/IF,FC
Recommended Dilution: WB: 1:1000
ICC/IF: 1:20
FC: 1:200
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human CCR8
Calculated Molecular Weight: 41 kDa
Observed Molecular Weight: 41 kDa
GenBank Accession Number: P51685
Gene ID (NCBI): 1237
Synonyms: CY6; TER1; CCR-8; CKRL1; CDw198; CMKBR8; GPRCY6; CMKBRL2; CC-CKR-8
Background: This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region. [provided by RefSeq, Jul 2008]
Category: Primary Ab
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