蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书ABCB11/BSEP Rabbit pAb
Cat#:DPA01448应用：IHC,ICC/IF,FC
| Product Name: | ABCB11/BSEP Rabbit pAb |
| Cat No.: | DPA01448 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | IHC,ICC/IF,FC |
| Recommended Dilution: | IHC: 1:50 ICC/IF: 1:50 FC: 1:50 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human ABCB11/BSEP |
| Calculated Molecular Weight: | 146 kDa |
| GenBank Accession Number: | O95342 |
| Gene ID (NCBI): | 8647 |
| Synonyms: | BSEP; PGY4; SPGP; ABC16; BRIC2; PFIC2; PFIC-2 |
| Background: | The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy. [provided by RefSeq, Jul 2008] |
| Category: | Primary Ab |
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