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查看说明书Recombinant Human Interleukin-6 receptor subunit alpha Protein
Cat#:TP05184应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | IL-6R Rabbit pAb |
| Cat No.: | DPA01458 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB,FC,IP |
| Recommended Dilution: | WB: 1:1000 FC: 1:20 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | Recombinant protein of human IL-6R |
| Calculated Molecular Weight: | 52 kDa |
| Observed Molecular Weight: | 40-80 kDa |
| GenBank Accession Number: | P08887 |
| Gene ID (NCBI): | 3570 |
| Synonyms: | IL6Q; gp80; CD126; IL6RA; IL6RQ; IL-6RA; IL-6R-1 |
| Background: | This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.[provided by RefSeq, May 2011] |
| Category: | Primary Ab |
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