Recombinant Human Lipopolysaccharide-Binding Protein Protein
Cat#:TP04895应用:Positive Control; Immunogen; SDS-PAGE; WB
Product Name: | LBP Rabbit pAb |
Cat No.: | DPA01462 |
Clonality: | Polyclonal |
Species Reactivity: | Human |
Tested Applications: | WB,IP |
Recommended Dilution: | WB: 1:1000 IP: 1:20 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human LBP |
Calculated Molecular Weight: | 53 kDa |
Observed Molecular Weight: | 53 kDa |
GenBank Accession Number: | P18428 |
Gene ID (NCBI): | 3929 |
Synonyms: | BPIFD2 |
Background: | The protein encoded by this gene is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal permeability-increasing protein (BPI), the encoded protein binds LPS and interacts with the CD14 receptor, probably playing a role in regulating LPS-dependent monocyte responses. Studies in mice suggest that the encoded protein is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation. This protein is part of a family of structurally and functionally related proteins, including BPI, plasma cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP). [provided by RefSeq, Apr 2012] |
Category: | Primary Ab |