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查看说明书Recombinant Human PRV1/CD177 Protein(C-6His)
Cat#:TP04888应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | CD177 Rabbit pAb |
| Cat No.: | DPA01463 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB,IHC |
| Recommended Dilution: | WB: 1:1000 IHC: 1:200 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | Recombinant protein of human CD177 |
| Calculated Molecular Weight: | 46 kDa |
| Observed Molecular Weight: | 70 kDa |
| GenBank Accession Number: | Q8N6Q3 |
| Gene ID (NCBI): | 57126 |
| Synonyms: | NB1; PRV1; HNA2A; PRV-1; HNA-2a; NB1 GP |
| Background: | This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener's granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified. [provided by RefSeq, Apr 2014] |
| Category: | Primary Ab |
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