蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书Slow Skeletal Myosin Heavy chain Rabbit pAb
Cat#:DPA01478应用：IHC
| Product Name: | Slow Skeletal Myosin Heavy chain Rabbit pAb |
| Cat No.: | DPA01478 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | IHC |
| Recommended Dilution: | IHC: 1:200 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human Slow Skeletal Myosin Heavy chain |
| Calculated Molecular Weight: | 224 kDa |
| GenBank Accession Number: | P12883 |
| Gene ID (NCBI): | 4625 |
| Synonyms: | CMH1; MPD1; SPMD; SPMM; CMD1S; MYHCB |
| Background: | Muscle myosin is a hexameric protein containing 2 heavy chain subunits, 2 alkali light chain subunits, and 2 regulatory light chain subunits. This gene encodes the beta (or slow) heavy chain subunit of cardiac myosin. It is expressed predominantly in normal human ventricle. It is also expressed in skeletal muscle tissues rich in slow-twitch type I muscle fibers. Changes in the relative abundance of this protein and the alpha (or fast) heavy subunit of cardiac myosin correlate with the contractile velocity of cardiac muscle. Its expression is also altered during thyroid hormone depletion and hemodynamic overloading. Mutations in this gene are associated with familial hypertrophic cardiomyopathy, myosin storage myopathy, dilated cardiomyopathy, and Laing early-onset distal myopathy. [provided by RefSeq, Jul 2008] |
| Category: | Primary Ab |
相关产品
