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LRP5 Rabbit pAb

Cat No.: DPA01489
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Product Name: LRP5 Rabbit pAb
Cat No.: DPA01489
Clonality: Polyclonal
Species Reactivity: Human, Mouse, Rat
Tested Applications: WB,IP
Recommended Dilution: WB: 1:1000
IP: 1:20
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: Recombinant protein of human LRP5
Calculated Molecular Weight: 179 kDa
Observed Molecular Weight: 200 kDa
GenBank Accession Number: O75197
Gene ID (NCBI): 4041
Synonyms: HBM; LR3; OPS; EVR1; EVR4; LRP7; OPPG; BMND1; LRP-5; LRP-7; OPTA1; PCLD4; VBCH2
Background: This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
Category: Primary Ab
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