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查看说明书Recombinant Human PLAUR Protein
Cat#:TP03433应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | uPA Receptor/U-PAR Rabbit pAb |
| Cat No.: | DPA01530 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | ICC/IF,FC,IP |
| Recommended Dilution: | ICC/IF: 1:20 FC: 1:50 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | Recombinant protein of human uPA Receptor/U-PAR |
| Calculated Molecular Weight: | 37 kDa |
| GenBank Accession Number: | Q03405 |
| Gene ID (NCBI): | 5329 |
| Synonyms: | CD87; UPAR; URKR; U-PAR |
| Background: | This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined. [provided by RefSeq, Jul 2008] |
| Category: | Primary Ab |
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