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查看说明书Desmoglein 1/DSG1 Rabbit pAb
Cat#:DPA01543应用：WB,IHC
| Product Name: | Desmoglein 1/DSG1 Rabbit pAb |
| Cat No.: | DPA01543 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB,IHC |
| Recommended Dilution: | WB: 1:1000 IHC: 1:50 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | Recombinant protein of human Desmoglein 1/DSG1 |
| Calculated Molecular Weight: | 114 kDa |
| Observed Molecular Weight: | 114 kDa |
| GenBank Accession Number: | Q02413 |
| Gene ID (NCBI): | 1828 |
| Synonyms: | DG1; DSG; CDHF4; EPKHE; PPKS1; SPPK1; EPKHIA |
| Background: | This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma. [provided by RefSeq, Feb 2015] |
| Category: | Primary Ab |
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