Recombinant Human SerpinI1 / Neuroserpin Protein (His tag)
Cat#:TP06786应用:Positive Control; Immunogen; SDS-PAGE; WB
Product Name: | Neuroserpin Rabbit pAb |
Cat No.: | DPA01644 |
Clonality: | Polyclonal |
Species Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB,IHC |
Recommended Dilution: | WB: 1:1000 IHC: 1:50 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | Recombinant protein of human Neuroserpin |
Calculated Molecular Weight: | 46 kDa |
Observed Molecular Weight: | 46 kDa |
GenBank Accession Number: | Q99574 |
Gene ID (NCBI): | 5274 |
Synonyms: | PI12; neuroserpin |
Background: | This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The protein is primarily secreted by axons in the brain, and preferentially reacts with and inhibits tissue-type plasminogen activator. It is thought to play a role in the regulation of axonal growth and the development of synaptic plasticity. Mutations in this gene result in familial encephalopathy with neuroserpin inclusion bodies (FENIB), which is a dominantly inherited form of familial encephalopathy and epilepsy characterized by the accumulation of mutant neuroserpin polymers. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008] |
Category: | Primary Ab |