Recombinant Human SerpinI1 / Neuroserpin Protein (His tag)
Cat#:TP06786应用:Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | Neuroserpin Rabbit pAb |
| Cat No.: | DPA01644 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB,IHC |
| Recommended Dilution: | WB: 1:1000 IHC: 1:50 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | Recombinant protein of human Neuroserpin |
| Calculated Molecular Weight: | 46 kDa |
| Observed Molecular Weight: | 46 kDa |
| GenBank Accession Number: | Q99574 |
| Gene ID (NCBI): | 5274 |
| Synonyms: | PI12; neuroserpin |
| Background: | This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The protein is primarily secreted by axons in the brain, and preferentially reacts with and inhibits tissue-type plasminogen activator. It is thought to play a role in the regulation of axonal growth and the development of synaptic plasticity. Mutations in this gene result in familial encephalopathy with neuroserpin inclusion bodies (FENIB), which is a dominantly inherited form of familial encephalopathy and epilepsy characterized by the accumulation of mutant neuroserpin polymers. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008] |
| Category: | Primary Ab |