ABCG5 Rabbit pAb
Cat#:DPA01649应用:WB
Product Name: | ABCG5 Rabbit pAb |
Cat No.: | DPA01649 |
Clonality: | Polyclonal |
Species Reactivity: | Human |
Tested Applications: | WB |
Recommended Dilution: | WB: 1:1000 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human ABCG5 |
Calculated Molecular Weight: | 73 kDa |
Observed Molecular Weight: | 73 kDa |
GenBank Accession Number: | Q9H222 |
Gene ID (NCBI): | 64240 |
Synonyms: | STSL; STSL2 |
Background: | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols. It is expressed in a tissue-specific manner in the liver, colon, and intestine. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG8. Mutations in this gene may contribute to sterol accumulation and atheroschlerosis, and have been observed in patients with sitosterolemia. [provided by RefSeq, Jul 2008] |
Category: | Primary Ab |