蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书HLA DMB Rabbit pAb
Cat#:DPA01652应用：WB,IHC,ICC/IF,IP
| Product Name: | HLA DMB Rabbit pAb |
| Cat No.: | DPA01652 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB,IHC,ICC/IF,IP |
| Recommended Dilution: | WB: 1:1000 IHC: 1:50 ICC/IF: 1:50 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human HLA DMB |
| Calculated Molecular Weight: | 29 kDa |
| Observed Molecular Weight: | 29 kDa |
| GenBank Accession Number: | P28068 |
| Gene ID (NCBI): | 3109 |
| Synonyms: | RING7; D6S221E |
| Background: | HLA-DMB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta (DMB) chain, both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP (class II-associated invariant chain peptide) molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. [provided by RefSeq, Jul 2008] |
| Category: | Primary Ab |
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