蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书Carma 1/CARD11 Rabbit pAb
Cat#:DPA01665应用：WB,ICC/IF
| Product Name: | Carma 1/CARD11 Rabbit pAb |
| Cat No.: | DPA01665 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse |
| Tested Applications: | WB,ICC/IF |
| Recommended Dilution: | WB: 1:1000 ICC/IF: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human Carma 1/CARD11 |
| Calculated Molecular Weight: | 133 kDa |
| Observed Molecular Weight: | 133 kDa |
| GenBank Accession Number: | Q9BXL7 |
| Gene ID (NCBI): | 84433 |
| Synonyms: | PPBL; BENTA; BIMP3; IMD11; CARMA1; IMD11A |
| Background: | The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. [provided by RefSeq, Jul 2008] |
| Category: | Primary Ab |
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