蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书mGluR1a Rabbit pAb
Cat#:DPA01668应用：WB
| Product Name: | mGluR1a Rabbit pAb |
| Cat No.: | DPA01668 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB |
| Recommended Dilution: | WB: 1:1000 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human mGluR1a |
| Calculated Molecular Weight: | 132 kDa |
| Observed Molecular Weight: | 125,250 kDa |
| GenBank Accession Number: | Q13255 |
| Gene ID (NCBI): | 2911 |
| Synonyms: | MGLU1; SCA44; GPRC1A; MGLUR1; SCAR13; PPP1R85 |
| Background: | This gene encodes a metabotropic glutamate receptor that functions by activating phospholipase C. L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The canonical alpha isoform of the encoded protein is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. This gene may be associated with many disease states, including schizophrenia, bipolar disorder, depression, and breast cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013] |
| Category: | Primary Ab |
相关产品
