蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书TAB3 Rabbit pAb
Cat#:DPA01720应用：WB,ICC/IF
| Product Name: | TAB3 Rabbit pAb |
| Cat No.: | DPA01720 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse |
| Tested Applications: | WB,ICC/IF |
| Recommended Dilution: | WB: 1:1000 ICC/IF: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human TAB3 |
| Calculated Molecular Weight: | 79 kDa |
| Observed Molecular Weight: | 82 kDa |
| GenBank Accession Number: | Q8N5C8 |
| Gene ID (NCBI): | 257397 |
| Synonyms: | NAP1; MAP3K7IP3 |
| Background: | The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008] |
| Category: | Primary Ab |
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