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nNOS (neuronal) Rabbit pAb

Cat No.: DPA01834
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Product Name: nNOS (neuronal) Rabbit pAb
Cat No.: DPA01834
Clonality: Polyclonal
Species Reactivity: Human, Mouse, Rat
Tested Applications: WB,ICC/IF,FC,IP
Recommended Dilution: WB: 1:1000
ICC/IF: 1:50
FC: 1:100
IP: 1:20
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human nNOS (neuronal)
Calculated Molecular Weight: 161 kDa
Observed Molecular Weight: 161 kDa
GenBank Accession Number: P29475
Gene ID (NCBI): 4842
Synonyms: NOS; bNOS; nNOS; IHPS1; N-NOS; NC-NOS
Background: The protein encoded by this gene belongs to the family of nitric oxide synthases, which synthesize nitric oxide from L-arginine. Nitric oxide is a reactive free radical, which acts as a biologic mediator in several processes, including neurotransmission, and antimicrobial and antitumoral activities. In the brain and peripheral nervous system, nitric oxide displays many properties of a neurotransmitter, and has been implicated in neurotoxicity associated with stroke and neurodegenerative diseases, neural regulation of smooth muscle, including peristalsis, and penile erection. This protein is ubiquitously expressed, with high level of expression in skeletal muscle. Multiple transcript variants that differ in the 5' UTR have been described for this gene but the full-length nature of these transcripts is not known. Additionally, alternatively spliced transcript variants encoding different isoforms (some testis-specific) have been found for this gene.[provided by RefSeq, Feb 2011]
Category: Primary Ab
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