Recombinant Human Azurocidin/CAP37/HBP Protein(C-6His)
Cat#:TP05442应用:Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | Azurocidin Rabbit pAb |
| Cat No.: | DPA01880 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB |
| Recommended Dilution: | WB: 1:1000 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human Azurocidin |
| Calculated Molecular Weight: | 27 kDa |
| Observed Molecular Weight: | 27 kDa |
| GenBank Accession Number: | P20160 |
| Gene ID (NCBI): | 566 |
| Synonyms: | AZU; HBP; NAZC; hHBP; AZAMP; CAP37; HUMAZUR |
| Background: | Azurophil granules, specialized lysosomes of the neutrophil, contain at least 10 proteins implicated in the killing of microorganisms. This gene encodes a preproprotein that is proteolytically processed to generate a mature azurophil granule antibiotic protein, with monocyte chemotactic and antimicrobial activity. It is also an important multifunctional inflammatory mediator. This encoded protein is a member of the serine protease gene family but it is not a serine proteinase, because the active site serine and histidine residues are replaced. The genes encoding this protein, neutrophil elastase 2, and proteinase 3 are in a cluster located at chromosome 19pter. All 3 genes are expressed coordinately and their protein products are packaged together into azurophil granules during neutrophil differentiation. [provided by RefSeq, Nov 2015] |
| Category: | Primary Ab |