Recombinant Human Interleukin-17 receptor A Protein
Cat#:TP04692应用:Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | IL-17RA Receptor Rabbit pAb |
| Cat No.: | DPA01932 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB |
| Recommended Dilution: | WB: 1:1000 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | Recombinant protein of human IL-17RA Receptor |
| Calculated Molecular Weight: | 96 kDa |
| Observed Molecular Weight: | 120-170 kDa |
| GenBank Accession Number: | Q96F46 |
| Gene ID (NCBI): | 23765 |
| Synonyms: | CD217; IL17R; IMD51; CANDF5; CDw217; IL-17RA; hIL-17R |
| Background: | Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2014] |
| Category: | Primary Ab |