Recombinant Human COMP Protein (His tag)
Cat#:TP07384应用:Positive Control; Immunogen; SDS-PAGE; WB
Product Name: | COMP/Cartilage oligomeric matrix protein Rabbit pAb |
Cat No.: | DPA01947 |
Clonality: | Polyclonal |
Species Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB,IP |
Recommended Dilution: | WB: 1:1000 IP: 1:20 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | Recombinant protein of human COMP/Cartilage oligomeric matrix protein |
Calculated Molecular Weight: | 83 kDa |
Observed Molecular Weight: | 110 kDa |
GenBank Accession Number: | P49747 |
Gene ID (NCBI): | 1311 |
Synonyms: | MED; EDM1; EPD1; TSP5; PSACH; THBS5 |
Background: | The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Contraction or expansion of a 5 aa aspartate repeat and other mutations can cause pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED). [provided by RefSeq, Jul 2016] |
Category: | Primary Ab |