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COMP/Cartilage oligomeric matrix protein Rabbit pAb

Cat No.: DPA01947
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Product Name: COMP/Cartilage oligomeric matrix protein Rabbit pAb
Cat No.: DPA01947
Clonality: Polyclonal
Species Reactivity: Human, Mouse, Rat
Tested Applications: WB,IP
Recommended Dilution: WB: 1:1000
IP: 1:20
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: Recombinant protein of human COMP/Cartilage oligomeric matrix protein
Calculated Molecular Weight: 83 kDa
Observed Molecular Weight: 110 kDa
GenBank Accession Number: P49747
Gene ID (NCBI): 1311
Synonyms: MED; EDM1; EPD1; TSP5; PSACH; THBS5
Background: The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Contraction or expansion of a 5 aa aspartate repeat and other mutations can cause pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED). [provided by RefSeq, Jul 2016]
Category: Primary Ab
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