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查看说明书Recombinant Protein Tyrosine Phosphatase Receptor Type N (PTPRN)
Cat#:TP05744应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | ICA 512/PTPRN Rabbit pAb |
| Cat No.: | DPA02010 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB,IHC,IP |
| Recommended Dilution: | WB: 1:1000 IHC: 1:100 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | Recombinant protein of human ICA 512/PTPRN |
| Calculated Molecular Weight: | 106 kDa |
| Observed Molecular Weight: | 106 kDa |
| GenBank Accession Number: | Q16849 |
| Gene ID (NCBI): | 5798 |
| Synonyms: | IA2; IA-2; ICA512; R-PTP-N; IA-2/PTP |
| Background: | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Dec 2010] |
| Category: | Primary Ab |
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