蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书Trk (pan) Rabbit pAb
Cat#:DPA02037应用：WB,IP
| Product Name: | Trk (pan) Rabbit pAb |
| Cat No.: | DPA02037 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB,IP |
| Recommended Dilution: | WB: 1:1000 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human Trk (pan) |
| Calculated Molecular Weight: | 88,92,94 kDa |
| Observed Molecular Weight: | 120-140 kDa |
| GenBank Accession Number: | P04629,Q16620,Q16288 |
| Gene ID (NCBI): | 4914,4915,4916 |
| Synonyms: | MTC; TRK; TRK1; TRKA; Trk-A; p140-TrkA |
| Background: | This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, cognitive disability and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. [provided by RefSeq, Jul 2008] |
| Category: | Primary Ab |
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