蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书p57 Kip2 Rabbit pAb
Cat#:DPA02169应用：WB,IHC,IP
| Product Name: | p57 Kip2 Rabbit pAb |
| Cat No.: | DPA02169 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB,IHC,IP |
| Recommended Dilution: | WB: 1:1000 IHC: 1:50 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human p57 Kip2 |
| Calculated Molecular Weight: | 32 kDa |
| Observed Molecular Weight: | 57 kDa |
| GenBank Accession Number: | P49918 |
| Gene ID (NCBI): | 1028 |
| Synonyms: | BWS; WBS; p57; BWCR; KIP2; p57Kip2 |
| Background: | This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010] |
| Category: | Primary Ab |
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