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检测试剂盒
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分子生物学
规格：
查看说明书Recombinant Human ITCH / AIP4 Protein (aa 526-903)
Cat#:TP06778应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | ITCH Rabbit pAb |
| Cat No.: | DPA02235 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB |
| Recommended Dilution: | WB: 1:1000 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human ITCH/AIP4 |
| Calculated Molecular Weight: | 103 kDa |
| Observed Molecular Weight: | 103 kDa |
| GenBank Accession Number: | Q96J02 |
| Gene ID (NCBI): | 83737 |
| Synonyms: | AIF4; AIP4; ADMFD; NAPP1 |
| Background: | This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein plays a role in multiple cellular processes including erythroid and lymphoid cell differentiation and the regulation of immune responses. Mutations in this gene are a cause of syndromic multisystem autoimmune disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012] |
| Category: | Primary Ab |
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