Ku70 Rabbit pAb
Cat#:DPA02241应用:WB,IHC,ICC/IF
| Product Name: | Ku70 Rabbit pAb |
| Cat No.: | DPA02241 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB,IHC,ICC/IF |
| Recommended Dilution: | WB: 1:2000-1:10000 IHC: 1:50 ICC/IF: 1:50 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human Ku70 |
| Calculated Molecular Weight: | 70 kDa |
| Observed Molecular Weight: | 70 kDa |
| GenBank Accession Number: | P12956 |
| Gene ID (NCBI): | 2547 |
| Synonyms: | ML8; KU70; TLAA; CTC75; CTCBF; G22P1 |
| Background: | The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq, Jul 2008] |
| Category: | Primary Ab |