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查看说明书Recombinant Thiopurine Methyltransferase (TPMT)
Cat#:TP04288应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | TPMT Rabbit pAb |
| Cat No.: | DPA02247 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB,IHC,ICC/IF,FC,IP |
| Recommended Dilution: | WB: 1:1000 IHC: 1:50 ICC/IF: 1:50 FC: 1:20-1:100 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human TPMT |
| Calculated Molecular Weight: | 28 kDa |
| Observed Molecular Weight: | 28 kDa |
| GenBank Accession Number: | P51580 |
| Gene ID (NCBI): | 7172 |
| Synonyms: | TPMTD |
| Background: | This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals, causing thiopurine S-methyltransferase deficiency. Related pseudogenes have been identified on chromosomes 3, 18 and X. [provided by RefSeq, Aug 2014] |
| Category: | Primary Ab |
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