蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书MBNL1 Rabbit pAb
Cat#:DPA02267应用：WB
| Product Name: | MBNL1 Rabbit pAb |
| Cat No.: | DPA02267 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse |
| Tested Applications: | WB |
| Recommended Dilution: | WB: 1:1000 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human MBNL1 |
| Calculated Molecular Weight: | 42 kDa |
| Observed Molecular Weight: | 42 kDa |
| GenBank Accession Number: | Q9NR56 |
| Gene ID (NCBI): | 4154 |
| Synonyms: | EXP; MBNL |
| Background: | This gene encodes a member of the muscleblind protein family which was initially described in Drosophila melanogaster. The encoded protein is a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Mice lacking this gene exhibited muscle abnormalities and cataracts. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined. The different isoforms are thought to have different binding specificities and/or splicing activities. [provided by RefSeq, Sep 2015] |
| Category: | Primary Ab |
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