XRCC1 Rabbit pAb
Cat#:DPA02336应用:WB,IHC,ICC/IF
| Product Name: | XRCC1 Rabbit pAb |
| Cat No.: | DPA02336 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB,IHC,ICC/IF |
| Recommended Dilution: | WB: 1:1000 IHC: 1:50 ICC/IF: 1:50 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human XRCC1 |
| Calculated Molecular Weight: | 70 kDa |
| Observed Molecular Weight: | 82 kDa |
| GenBank Accession Number: | P18887 |
| Gene ID (NCBI): | 7515 |
| Synonyms: | RCC; SCAR26 |
| Background: | The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008] |
| Category: | Primary Ab |