蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书APC Rabbit pAb
Cat#:DPA02394应用：WB,IHC,ICC/IF,FC,IP
| Product Name: | APC Rabbit pAb |
| Cat No.: | DPA02394 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Rat |
| Tested Applications: | WB,IHC,ICC/IF,FC,IP |
| Recommended Dilution: | WB: 1:1000 IHC: 1:20 ICC/IF: 1:20 FC: 1:20 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human APC |
| Calculated Molecular Weight: | 312 kDa |
| Observed Molecular Weight: | 160 kDa |
| GenBank Accession Number: | P25054 |
| Gene ID (NCBI): | 324 |
| Synonyms: | GS; DP2; DP3; BTPS2; DESMD; DP2.5; PPP1R46 |
| Background: | This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Mutations in the APC gene have been found to occur in most colorectal cancers. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. [provided by RefSeq, Dec 2019] |
| Category: | Primary Ab |
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