蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书APLP2 Rabbit pAb
Cat#:DPA02429应用：WB,IHC
| Product Name: | APLP2 Rabbit pAb |
| Cat No.: | DPA02429 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB,IHC |
| Recommended Dilution: | WB: 1:2000-1:10000 IHC: 1:50 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human APLP2 |
| Calculated Molecular Weight: | 87 kDa |
| Observed Molecular Weight: | 115 kDa |
| GenBank Accession Number: | Q06481 |
| Gene ID (NCBI): | 334 |
| Synonyms: | APPH; APPL2; CDEBP; APLP-2 |
| Background: | This gene encodes amyloid precursor- like protein 2 (APLP2), which is a member of the APP (amyloid precursor protein) family including APP, APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at the N-terminus, BPTI/Kunitz inhibitor and E2 domains in the middle region, and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission, spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer's disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011] |
| Category: | Primary Ab |
相关产品
