Recombinant Human Centrosomal protein 43 (FGFR1OP)
Cat#:TP02123应用:Positive Control; Immunogen; SDS-PAGE; WB
Product Name: | FGFR1 Oncogene Partner Rabbit pAb |
Cat No.: | DPA02440 |
Clonality: | Polyclonal |
Species Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB,ICC/IF,FC,IP |
Recommended Dilution: | WB: 1:1000 ICC/IF: 1:50 FC: 1:20-1:100 IP: 1:20 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human FGFR1 Oncogene Partner |
Calculated Molecular Weight: | 43 kDa |
Observed Molecular Weight: | 43 kDa |
GenBank Accession Number: | O95684 |
Gene ID (NCBI): | 11116 |
Synonyms: | FOP; FGFR1OP |
Background: | This gene encodes a largely hydrophilic centrosomal protein that is required for anchoring microtubules to subcellular structures. A t(6;8)(q27;p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. Alterations in this gene may also be associated with Crohn's disease, Graves' disease, and vitiligo. Alternatively spliced transcript variants that encode different proteins have been identified. [provided by RefSeq, Jul 2013] |
Category: | Primary Ab |