HLA-DQA1 Rabbit pAb
Cat#:DPA02519应用:WB,IHC,IP
Product Name: | HLA-DQA1 Rabbit pAb |
Cat No.: | DPA02519 |
Clonality: | Polyclonal |
Species Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB,IHC,IP |
Recommended Dilution: | WB: 1:2000-1:10000 IHC: 1:50 IP: 1:20 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human HLA-DQA1 |
Calculated Molecular Weight: | 28 kDa |
Observed Molecular Weight: | 28-35 kDa |
GenBank Accession Number: | P01909 |
Synonyms: | DC-1 alpha chain; DC-alpha; HLA-DCA; MHC class II DQA1 |
Background: | Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class II molecules are generated mostly by degradation of proteins that access the endocytic route, where they are processed by lysosomal proteases and other hydrolases. |
Category: | Primary Ab |