NDUFA1 Rabbit pAb
Cat#:DPA02583应用:WB,IHC,IP
Product Name: | NDUFA1 Rabbit pAb |
Cat No.: | DPA02583 |
Clonality: | Polyclonal |
Species Reactivity: | Human |
Tested Applications: | WB,IHC,IP |
Recommended Dilution: | WB: 1:1000 IHC: 1:50 IP: 1:20 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human NDUFA1 |
Calculated Molecular Weight: | 8 kDa |
Observed Molecular Weight: | 8 kDa |
GenBank Accession Number: | O15239 |
Gene ID (NCBI): | 4694 |
Synonyms: | MWFE; ZNF183; CI-MWFE; MC1DN12 |
Background: | The human NDUFA1 gene codes for an essential component of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. It has been noted that the N-terminal hydrophobic domain has the potential to be folded into an alpha-helix spanning the inner mitochondrial membrane with a C-terminal hydrophilic domain interacting with globular subunits of complex I. The highly conserved two-domain structure suggests that this feature is critical for the protein function and might act as an anchor for the NADH:ubiquinone oxidoreductase complex at the inner mitochondrial membrane. However, the NDUFA1 peptide is one of about 31 components of the "hydrophobic protein" (HP) fraction of complex I which is involved in proton translocation. Thus the NDUFA1 peptide may also participate in that function. [provided by RefSeq, Jul 2008] |
Category: | Primary Ab |