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hnRNP G-T Rabbit pAb

Cat No.: DPA02591
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Product Name: hnRNP G-T Rabbit pAb
Cat No.: DPA02591
Clonality: Polyclonal
Species Reactivity: Human, Mouse, Rat
Tested Applications: WB,ICC/IF,IP
Recommended Dilution: WB: 1:2000-1:10000
ICC/IF: 1:50
IP: 1:20
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: Recombinant protein of human hnRNP G-T
Calculated Molecular Weight: 43 kDa
Observed Molecular Weight: 43 kDa
GenBank Accession Number: O75526
Gene ID (NCBI): 27288
Synonyms: HNRPGT; HNRNPGT; HNRNPG-T
Background: This gene belongs to the HNRPG subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two RRM domains that bind RNAs. This gene is intronless and is thought to be derived from a processed retroposon. However, unlike many retroposon-derived genes, this gene is not a pseudogene. The encoded protein has similarity to HNRPG and RBMY proteins and it is suggested to replace HNRPG protein function during meiotic prophase or act as a germ cell-specific splicing regulator. It primarily localizes to the nuclei of meiotic spermatocytes. This gene is a candidate for autosomal male infertility. [provided by RefSeq, Jul 2008]
Category: Primary Ab
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